Dynamic expression of long non-coding RNAs (lncRNAs) in adult zebrafish.

ABSTRACT: Long non-coding RNAs (lncRNA) represent an assorted class of transcripts having little or no protein coding capacity and have recently gained importance for their function as regulators of gene expression. Molecular studies on lncRNA have uncovered multifaceted interactions with protein coding genes. It has been suggested that lncRNAs are an additional layer of regulatory switches involved in gene regulation during development and disease. LncRNAs expressing in specific tissues or cell types during adult stages can have potential roles in form, function, maintenance and repair of tissues and organs. We used RNA sequencing followed by computational analysis to identify tissue restricted lncRNA transcript signatures from five different tissues of adult zebrafish. The present study reports 44

SUBMITTER: Kaushik K 

PROVIDER: S-EPMC3877055 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature