Lactococcus garvieae: where is it from? A first approach to explore the evolutionary history of this emerging pathogen.

ABSTRACT: The population structure and diversity of Lactococcus garvieae, an emerging pathogen of increasing clinical significance, was determined at both gene and genome level. Selected lactococcal isolates of various origins were analyzed by a multi locus sequence typing (MLST). This gene-based analysis was compared to genomic characteristics, estimated through the complete genome sequences available in database. The MLST identified two branches containing the majority of the strains and two branches bearing one strain each. One strain was particularly differentiated from the other L. garvieae strains, showing a significant genetic distance. The genomic characteristics, correlated to the MLST-based phylogeny, indicated that this "separated strain" appeared first and could be considered the evoluti

SUBMITTER: Ferrario C 

PROVIDER: S-EPMC3877359 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature