A genome-wide scan for signatures of differential artificial selection in ten cattle breeds.

ABSTRACT:

Background

Since the times of domestication, cattle have been continually shaped by the influence of humans. Relatively recent history, including breed formation and the still enduring enormous improvement of economically important traits, is expected to have left distinctive footprints of selection within the genome. The purpose of this study was to map genome-wide selection signatures in ten cattle breeds and thus improve the understanding of the genome response to strong artificial selection and support the identification of the underlying genetic variants of favoured phenotypes. We analysed 47,651 single nucleotide polymorphisms (SNP) using Cross Population Extended Haplotype Homozygosity (XP-EHH).

Results

We set the significance thresholds using the maximum XP-EHH value

SUBMITTER: Rothammer S 

PROVIDER: S-EPMC3878089 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature