Association of microsatellite pairs with segmental duplications in insect genomes.

ABSTRACT:

Background

Segmental duplications (SDs), also known as low-copy repeats, are DNA sequences of length greater than 1 kb which are duplicated with a high degree of sequence identity (greater than 90%) causing instability in genomes. SDs are generally found in the genome as mosaic forms of duplicated sequences which are generated by a two-step process: first, multiple duplicated sequences are aggregated at specific genomic regions, and then, these primary duplications undergo multiple secondary duplications. However, the mechanism of how duplicated sequences are aggregated in the first place is not well understood.

Results

By analyzing the distribution of microsatellite sequences among twenty insect species in a genome-wide manner it was found that pairs of microsatellites alon

SUBMITTER: Behura SK 

PROVIDER: S-EPMC3878106 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature