Consumption of chocolate in pregnant women and risk of preeclampsia: a systematic review.

ABSTRACT:

Background

Previous studies have been limited in reporting the association between chocolate consumption, measured by interviewer-administered questionnaire or serum theobromine, a biomarker for cocoa, and risk of preeclampsia, and have showed somewhat conflicting results.

Methods/design

A systematic review of observational and experimental studies will be carried out. We will examine PubMed, Embase, and the entire Cochrane Library. Studies of chocolate consumption compared or not with placebo or low flavanol chocolate during pregnancy will be evaluated to investigate the effect of chocolate consumption in pregnant women on the risk of preeclampsia or pregnancy-induced hypertension. Screening for inclusion, data extraction, and quality assessment will be performed independen

SUBMITTER: Mogollon JA 

PROVIDER: S-EPMC3878223 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature