Reproducibility of small animal cine and scar cardiac magnetic resonance imaging using a clinical 3.0 tesla system.

ABSTRACT:

Background

To evaluate the inter-study, inter-reader and intra-reader reproducibility of cardiac cine and scar imaging in rats using a clinical 3.0 Tesla magnetic resonance (MR) system.

Methods

Thirty-three adult rats (Sprague-Dawley) were imaged 24 hours after surgical occlusion of the left anterior descending coronary artery using a 3.0 Tesla clinical MR scanner (Philips Healthcare, Best, The Netherlands) equipped with a dedicated 70 mm solenoid receive-only coil. Left-ventricular (LV) volumes, mass, ejection fraction and amount of myocardial scar tissue were measured. Intra-and inter-observer reproducibility was assessed in all animals. In addition, repeat MR exams were performed in 6 randomly chosen rats within 24 hours to assess inter-study reproducibility.

Results</

SUBMITTER: Manka R 

PROVIDER: S-EPMC3878577 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature