Association between GFR estimated by multiple methods at dialysis commencement and patient survival.

ABSTRACT:

Background and objectives

The Initiating Dialysis Early and Late study showed that planned early or late initiation of dialysis, based on the Cockcroft and Gault estimation of GFR, was associated with identical clinical outcomes. This study examined the association of all-cause mortality with estimated GFR at dialysis commencement, which was determined using multiple formulas.

Design, setting, participants, & measurements

Initiating Dialysis Early and Late trial participants were stratified into tertiles according to the estimated GFR measured by Cockcroft and Gault, Modification of Diet in Renal Disease, or Chronic Kidney Disease-Epidemiology Collaboration formula at dialysis commencement. Patient survival was determined using multivariable Cox proportional hazards model re

SUBMITTER: Wong MG 

PROVIDER: S-EPMC3878691 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature