Dietary phthalates and low-grade albuminuria in US children and adolescents.

ABSTRACT:

Background

Low-grade albuminuria is an indicator of endothelial dysfunction and is associated with an increased risk of cardiovascular disease. A graded level of exposure to bisphenol A was recently identified to be associated with increased risk of low-grade albuminuria in children and adults. Because bisphenol A and phthalates coexist as dietary contaminants, this study investigated whether exposure to phthalates is also associated with low-grade albuminuria.

Design, setting, participants, & measurements

Data were examined from 667 children who participated in the 2009-2010 National Health and Nutrition Examination Survey and who had results for urinary phthalate metabolites and albumin excretion. Urinary albumin and creatinine concentrations were measured in a first morni

SUBMITTER: Trasande L 

PROVIDER: S-EPMC3878700 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature