A deep insight into the sialotranscriptome of the mosquito, Psorophora albipes.

ABSTRACT:

Background

Psorophora mosquitoes are exclusively found in the Americas and have been associated with transmission of encephalitis and West Nile fever viruses, among other arboviruses. Mosquito salivary glands represent the final route of differentiation and transmission of many parasites. They also secrete molecules with powerful pharmacologic actions that modulate host hemostasis, inflammation, and immune response. Here, we employed next generation sequencing and proteome approaches to investigate for the first time the salivary composition of a mosquito member of the Psorophora genus. We additionally discuss the evolutionary position of this mosquito genus into the Culicidae family by comparing the identity of its secreted salivary compounds to other mosquito salivary proteins id

SUBMITTER: Chagas AC 

PROVIDER: S-EPMC3878727 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature