Stochastic flux analysis of chemical reaction networks.

ABSTRACT:

Background

Chemical reaction networks provide an abstraction scheme for a broad range of models in biology and ecology. The two common means for simulating these networks are the deterministic and the stochastic approaches. The traditional deterministic approach, based on differential equations, enjoys a rich set of analysis techniques, including a treatment of reaction fluxes. However, the discrete stochastic simulations, which provide advantages in some cases, lack a quantitative treatment of network fluxes.

Results

We describe a method for flux analysis of chemical reaction networks, where flux is given by the flow of species between reactions in stochastic simulations of the network. Extending discrete event simulation algorithms, our method constructs several data struc

SUBMITTER: Kahramanogulları O 

PROVIDER: S-EPMC3878955 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature