Feasibility of image-guided transthoracic core-needle biopsy in the BATTLE lung trial.

ABSTRACT:

Background

As therapy for non-small-cell lung cancer (NSCLC) patients becomes more personalized, additional tissue in the form of core-needle biopsies (CNBs) for biomarker analysis is increasingly required for determining appropriate treatment and for enrollment into clinical trials. We report our experience with small-caliber percutaneous transthoracic (PT) CNBs for the evaluation of multiple molecular biomarkers in BATTLE (biomarker-integrated approaches of targeted therapy for lung cancer elimination), a personalized, targeted therapy NSCLC clinical trial.

Methods

The medical records of patients who underwent PTCNB for consideration of enrollment in BATTLE were reviewed for diagnostic yield of 11 predetermined molecular markers and procedural complications. Univariate and

SUBMITTER: Tam AL 

PROVIDER: S-EPMC3879952 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature