Emotional face processing in pediatric bipolar disorder: evidence for functional impairments in the fusiform gyrus.

ABSTRACT:

Objective

Pediatric bipolar disorder involves poor social functioning, but the neural mechanisms underlying these deficits are not well understood. Previous neuroimaging studies have found deficits in emotional face processing localized to emotional brain regions. However, few studies have examined dysfunction in other regions of the face processing circuit. This study assessed hypoactivation in key face processing regions of the brain in pediatric bipolar disorder.

Method

Youth with a bipolar spectrum diagnosis (n = 20) were matched to a nonbipolar clinical group (n = 20), with similar demographics and comorbid diagnoses, and a healthy control group (n = 20). Youth participated in a functional magnetic resonance imaging (fMRI) scanning which employed a task-irrelevant emoti

SUBMITTER: Perlman SB 

PROVIDER: S-EPMC3881180 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature