Intercepting the synthesis of triazine dendrimers with nucleophilic pharmacophores: a general strategy toward drug delivery vehicles.

ABSTRACT: The camptothecin ester of isonipecotic acid is installed on a triazine dendrimer intermediate obtained through an iterative, scalable route to ultimately yield cationic and PEGylated targets with activities in cell culture comparable to free drug.

SUBMITTER: Venditto VJ 

PROVIDER: S-EPMC3881288 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature