The metabolic syndrome and neuropathy: therapeutic challenges and opportunities.

ABSTRACT: The metabolic syndrome and neuropathy are common conditions, especially in the elderly, that are associated with significant morbidity. Furthermore, the metabolic syndrome is reaching epidemic proportions across the world. Current evidence supports the association of the metabolic syndrome and its individual components with neuropathy. Several clinical trials have demonstrated that treating hyperglycemia, a component of the metabolic syndrome, has a significant effect on reducing the incidence of neuropathy in those with type 1 diabetes. However, glucose control has only a marginal effect on preventing neuropathy in those with type 2 diabetes, suggesting that other factors may be driving nerve injury in these patients. Emerging evidence supports the metabolic syndrome as including risk fac

SUBMITTER: Callaghan B 

PROVIDER: S-EPMC3881591 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature