Oxime cross-linked injectable hydrogels for catheter delivery.

ABSTRACT: Catheter delivery of therapeutic materials is important for developing minimally invasive treatment approaches. However, the majority of injectable materials gel rapidly upon mixing and/or heating to body temperature. The application of an oxime cross-linked hydrogel system is demonstrated. The system has a broad range of tunable gelation rates, is capable of injection through a catheter, and exhibits rapid gelation upon injection into tissue.

SUBMITTER: Grover GN 

PROVIDER: S-EPMC3884068 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature