TIPMaP: a web server to establish transcript isoform profiles from reliable microarray probes.

ABSTRACT:

Background

Standard 3' Affymetrix gene expression arrays have contributed a significantly higher volume of existing gene expression data than other microarray platforms. These arrays were designed to identify differentially expressed genes, but not their alternatively spliced transcript forms. No resource can currently identify expression pattern of specific mRNA forms using these microarray data, even though it is possible to do this.

Results

We report a web server for expression profiling of alternatively spliced transcripts using microarray data sets from 31 standard 3' Affymetrix arrays for human, mouse and rat species. The tool has been experimentally validated for mRNAs transcribed or not-detected in a human disease condition (non-obstructive azoospermia, a male infert

SUBMITTER: Chitturi N 

PROVIDER: S-EPMC3884118 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature