Genetic admixture and obesity: recent perspectives and future applications.

ABSTRACT: The process of the colonization of the New World that occurred centuries ago served as a natural experiment, creating unique combinations of genetic material in newly formed admixed populations. Through a genetic admixture approach, the identification and genotyping of ancestry informative markers have allowed for the estimation of proportions of ancestral parental populations among individuals in a sample. These admixture estimates have been used in different ways to understand the genetic contributions to individual variation in obesity and body composition parameters, particularly among diverse admixed groups known to differ in obesity prevalence within the United States. Although progress has been made through the use of genetic admixture approaches, further investigations are needed i

SUBMITTER: Fernandez JR 

PROVIDER: S-EPMC3884567 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature