Metastatic melanoma - a review of current and future drugs.

ABSTRACT:

Background

Melanoma is one of the most aggressive cancers, and it is estimated that 76,250 men and women will be diagnosed with melanoma of the skin in the USA in 2012. Over the last few decades many drugs have been developed but only in 2011 have new drugs demonstrated an impact on survival in metastatic melanoma.

Methods

A systematic search of literature was conducted, and studies providing data on the effectiveness of current and/or future drugs used in the treatment of metastatic melanoma were selected for review. This review discusses the advantages and limitations of these agents, evaluating past, current and future clinical trials designed to overcome such limitations.

Results

To date, there are four drugs approved by the Food and Drug Administration for melano

SUBMITTER: Velho TR 

PROVIDER: S-EPMC3885142 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature