Social deprivation, inequality, and the neighborhood-level incidence of psychotic syndromes in East London.

ABSTRACT: Although urban birth, upbringing, and living are associated with increased risk of nonaffective psychotic disorders, few studies have used appropriate multilevel techniques accounting for spatial dependency in risk to investigate social, economic, or physical determinants of psychosis incidence. We adopted Bayesian hierarchical modeling to investigate the sociospatial distribution of psychosis risk in East London for DSM-IV nonaffective and affective psychotic disorders, ascertained over a 2-year period in the East London first-episode psychosis study. We included individual and environmental data on 427 subjects experiencing first-episode psychosis to estimate the incidence of disorder across 56 neighborhoods, having standardized for age, sex, ethnicity, and socioeconomic status. A Bayesi

SUBMITTER: Kirkbride JB 

PROVIDER: S-EPMC3885290 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature