Chiral β-Iodoamines by Urea-Catalyzed Iodocyclization of Trichloroacetimidates.

ABSTRACT: Highly enantioselective vicinal iodoamination of olefins is accomplished through the iodocyclization of alkenyl trichloroacetimidates catalyzed by a new chiral Schiff-base urea derivative. The resulting products are converted readily to a variety of polyfunctional amine-containing chiral building blocks.

SUBMITTER: Brindle CS 

PROVIDER: S-EPMC3885344 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature