Simultaneous functional photoacoustic and ultrasonic endoscopy of internal organs in vivo.

ABSTRACT: At present, clinicians routinely apply ultrasound endoscopy in a variety of interventional procedures that provide treatment solutions for diseased organs. Ultrasound endoscopy not only produces high-resolution images, but also is safe for clinical use and broadly applicable. However, for soft tissue imaging, its mechanical wave-based image contrast fundamentally limits its ability to provide physiologically specific functional information. By contrast, photoacoustic endoscopy possesses a unique combination of functional optical contrast and high spatial resolution at clinically relevant depths, ideal for imaging soft tissues. With these attributes, photoacoustic endoscopy can overcome the current limitations of ultrasound endoscopy. Moreover, the benefits of photoacoustic imaging do not c

SUBMITTER: Yang JM 

PROVIDER: S-EPMC3885361 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature