Massively parallel sequencing of Chikso (Korean brindle cattle) to discover genome-wide SNPs and InDels.

ABSTRACT: Since the completion of the bovine sequencing projects, a substantial number of genetic variations such as single nucleotide polymorphisms have become available across the cattle genome. Recently, cataloguing such genetic variations has been accelerated using massively parallel sequencing technology. However, most of the recent studies have been concentrated on European Bos taurus cattle breeds, resulting in a severe lack of knowledge for valuable native cattle genetic resources worldwide. Here, we present the first whole-genome sequencing results for an endangered Korean native cattle breed, Chikso, using the Illumina HiSeq 2,000 sequencing platform. The genome of a Chikso bull was sequenced to approximately 25.3-fold coverage with 98.8% of the bovine reference genome sequence (UMD 3.1) c

SUBMITTER: Choi JW 

PROVIDER: S-EPMC3887973 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature