Incidence and prevalence of multiple sclerosis in the UK 1990-2010: a descriptive study in the General Practice Research Database.

ABSTRACT:

Objectives

To estimate the incidence and prevalence of multiple sclerosis (MS) by age and describe secular trends and geographic variations within the UK over the 20-year period between 1990 and 2010 and hence to provide updated information on the impact of MS throughout the UK.

Design

A descriptive study.

Setting

The study was carried out in the General Practice Research Database (GPRD), a primary care database representative of the UK population.

Main outcome measures

Incidence and prevalence of MS per 100 000 population. Secular and geographical trends in incidence and prevalence of MS.

Results

The prevalence of MS recorded in GPRD increased by about 2.4% per year (95% CI 2.3% to 2.6%) reaching 285.8 per 100 000 in women (95% CI 278.7 to 293.1) and 11

SUBMITTER: Mackenzie IS 

PROVIDER: S-EPMC3888639 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature