Mechanical and electrokinetic effects of polyamines/phospholipid interactions in model membranes.

ABSTRACT: The mechanical and electrical properties of phospholipids layers influenced by interaction with polyamines were determined by measuring surface pressure and compression modulus of monolayers and zeta potential of liposomes. The saturated derivative of phosphatidic acid (DPPA) formed layers of the organization varying with compression degree. Contact of DPPA layers with polyamines present in the subphase resulted in changing their mechanical properties and the conditions in which the layer reorganization appears. The parameters corresponding to the layer reorganization depended on the size and charge of polyamines' molecules. The values of: area per DPPA molecule, surface pressure at the point of layer structure reorganization, and surface pressure at the point of collapse characterizing of

SUBMITTER: Rudolphi-Skorska E 

PROVIDER: S-EPMC3889835 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature