The neuropeptide complement of the marine annelid Platynereis dumerilii.

ABSTRACT:

Background

The marine annelid Platynereis dumerilii is emerging as a powerful lophotrochozoan experimental model for evolutionary developmental biology (evo-devo) and neurobiology. Recent studies revealed the presence of conserved neuropeptidergic signaling in Platynereis, including vasotocin/neurophysin, myoinhibitory peptide and opioid peptidergic systems. Despite these advances, comprehensive peptidome resources have yet to be reported.

Results

The present work describes the neuropeptidome of Platynereis. We established a large transcriptome resource, consisting of stage-specific next-generation sequencing datasets and 77,419 expressed sequence tags. Using this information and a combination of bioinformatic searches and mass spectrometry analyses, we increased the known p

SUBMITTER: Conzelmann M 

PROVIDER: S-EPMC3890597 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature