Cervical screening at age 50-64 years and the risk of cervical cancer at age 65 years and older: population-based case control study.

ABSTRACT:

Background

There is little consensus, and minimal evidence, regarding the age at which to stop cervical screening. We studied the association between screening at age 50-64 y and cervical cancer at age 65-83 y.

Methods and findings

Cases were women (n = 1,341) diagnosed with cervical cancer at age 65-83 y between 1 April 2007 and 31 March 2012 in England and Wales; age-matched controls (n = 2,646) were randomly selected from population registers. Screening details from 1988 onwards were extracted from national databases. We calculated the odds ratios (OR) for different screening histories and subsequent cervical cancer. Women with adequate negative screening at age 65 y (288 cases, 1,395 controls) were at lowest risk of cervical cancer (20-y risk: 8 cancers per 10,000 women)

SUBMITTER: Castanon A 

PROVIDER: S-EPMC3891624 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature