Refining a Jagged edge.

ABSTRACT: In a recent Cell Reports article, Chillakuri and colleagues showed that the N-terminal "MNNL" domain of the essential Notch ligand Jagged1 resembles a C2 domain and relies on calcium binding to facilitate productive signal transduction.

SUBMITTER: Blacklow SC 

PROVIDER: S-EPMC3892149 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature