Survival after diagnosis of localized T1a kidney cancer: current population-based practice of surgery and nonsurgical management.

ABSTRACT:

Objective

To compare overall and cancer-specific survival (CSS) of patients who undergo nonsurgical management (NSM), partial nephrectomy (PN), and radical nephrectomy (RN). NSM is being increasingly used for older patients with early-stage kidney cancer and competing risks of death. However, survival is poorly characterized for this approach compared with surgery with PN or RN.

Methods

The Surveillance, Epidemiology and End Results-Medicare database from 1995 to 2007 was used to identify patients aged 65 years or older diagnosed with localized T1a kidney cancer treated with PN, RN, or NSM. We used Cox proportional hazards regression, Fine and Gray competing risks regression, and propensity score matching to adjust for patient and tumor characteristics.

Results

Of 717

SUBMITTER: Patel HD 

PROVIDER: S-EPMC3892770 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature