Adherence to artemisinin-based combination therapy for the treatment of malaria: a systematic review of the evidence.

ABSTRACT:

Background

Increasing access to and targeting of artemisinin-based combination therapy (ACT) is a key component of malaria control programmes. To maximize efficacy of ACT and ensure adequate treatment outcomes, patient and caregiver adherence to treatment guidelines is essential. This review summarizes the current evidence base on ACT adherence, including definitions, measurement methods, and associated factors.

Methods

A systematic search of the published literature was undertaken in November 2012 and updated in April 2013. Bibliographies of manuscripts were also searched and additional references identified. Studies were included if they involved at least one form of ACT and reported an adherence measurement.

Results

The search yielded 1,412 records, 37 of which wer

SUBMITTER: Banek K 

PROVIDER: S-EPMC3893456 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature