Skylign: a tool for creating informative, interactive logos representing sequence alignments and profile hidden Markov models.

ABSTRACT:

Background

Logos are commonly used in molecular biology to provide a compact graphical representation of the conservation pattern of a set of sequences. They render the information contained in sequence alignments or profile hidden Markov models by drawing a stack of letters for each position, where the height of the stack corresponds to the conservation at that position, and the height of each letter within a stack depends on the frequency of that letter at that position.

Results

We present a new tool and web server, called Skylign, which provides a unified framework for creating logos for both sequence alignments and profile hidden Markov models. In addition to static image files, Skylign creates a novel interactive logo plot for inclusion in web pages. These interactive l

SUBMITTER: Wheeler TJ 

PROVIDER: S-EPMC3893531 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature