MUbiSiDa: a comprehensive database for protein ubiquitination sites in mammals.

ABSTRACT:

Motivation

Protein ubiquitination is one of the important post-translational modifications by attaching ubiquitin to specific lysine (K) residues in target proteins, and plays important regulatory roles in many cell processes. Recent studies indicated that abnormal protein ubiquitination have been implicated in many diseases by degradation of many key regulatory proteins including tumor suppressor, oncoprotein, and cell cycle regulator. The detailed information of protein ubiquitination sites is useful for scientists to investigate the mechanism of many cell activities and related diseases.

Results

In this study we established mUbiSida for mammalian Ubiquitination Site Database, which provides a scientific community with a comprehensive, freely and high-quality accessible re

SUBMITTER: Chen T 

PROVIDER: S-EPMC3894998 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature