Cerebellar morphology and the effects of stimulant medications in youths with attention deficit-hyperactivity disorder.

ABSTRACT: The cerebellum is emerging as a key anatomical structure underlying normal attentional and cognitive control mechanisms. Dysregulation within cerebellar circuits may contribute to the core symptoms of Attention Deficit/Hyperactivity Disorder (ADHD). In the present study we aimed to characterize surface morphological features of the cerebellum in ADHD and healthy comparison youths. Further, we studied the association of cerebellar morphology with the severity of ADHD symptoms and the effects of stimulant treatment. We examined 46 youths with ADHD and 59 comparison youths 8-18 years of age in a cross-sectional, case-control study using magnetic resonance imaging. Measures of cerebellar surface morphology were the primary outcome. Relative to comparison participants, youths with ADHD exhibite

SUBMITTER: Ivanov I 

PROVIDER: S-EPMC3895250 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature