Ventral striatum gray matter density reduction in patients with schizophrenia and psychotic emotional dysregulation.

ABSTRACT:

Introduction

Substantial heterogeneity remains across studies investigating changes in gray matter in schizophrenia. Differences in methodology, heterogeneous symptom patterns and symptom trajectories may contribute to inconsistent findings. To address this problem, we recently proposed to group patients by symptom dimensions, which map on the language, the limbic and the motor systems. The aim of the present study was to investigate whether patients with prevalent symptoms of emotional dysregulation would show structural neuronal abnormalities in the limbic system.

Method

43 right-handed medicated patients with schizophrenia were assessed with the Bern Psychopathology Scale (BPS). The patients and a control group of 34 healthy individuals underwent structural imaging at a 3

SUBMITTER: Stegmayer K 

PROVIDER: S-EPMC3895617 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature