Functional brain imaging studies of youth depression: a systematic review.

ABSTRACT:

Background

There is growing interest in understanding the neurobiology of major depressive disorder (MDD) in youth, particularly in the context of neuroimaging studies. This systematic review provides a timely comprehensive account of the available functional magnetic resonance imaging (fMRI) literature in youth MDD.

Methods

A literature search was conducted using PubMED, PsycINFO and Science Direct databases, to identify fMRI studies in younger and older youth with MDD, spanning 13-18 and 19-25 years of age, respectively.

Results

Twenty-eight studies focusing on 5 functional imaging domains were identified, namely emotion processing, cognitive control, affective cognition, reward processing and resting-state functional connectivity. Elevated activity in "extended med

SUBMITTER: Kerestes R 

PROVIDER: S-EPMC3895619 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature