Phylogenetic and biological significance of evolutionary elements from metazoan mitochondrial genomes.

ABSTRACT: The evolutionary history of living species is usually inferred through the phylogenetic analysis of molecular and morphological information using various mathematical models. New challenges in phylogenetic analysis are centered mostly on the search for accurate and efficient methods to handle the huge amounts of sequence data generated from newer genome sequencing. The next major challenge is the determination of relationships between the evolution of structural elements and their functional implementation, which is largely ignored in previous analyses. Here, we described the discovery of structural elements in metazoan mitochondrial genomes, termed key K-strings, that can serve as a basis for phylogenetic tree construction. Although comprising only a small fraction (0.73%) of all K-string

SUBMITTER: Yuan J 

PROVIDER: S-EPMC3896360 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature