Validation of PhenX measures in the personalized medicine research project for use in gene/environment studies.

ABSTRACT:

Background

The purpose of this paper is to describe the data collection efforts and validation of PhenX measures in the Personalized Medicine Research Project (PMRP) cohort.

Methods

Thirty-six measures were chosen from the PhenX Toolkit within the following domains: demographics; anthropometrics; alcohol, tobacco and other substances; cardiovascular; environmental exposures; cancer; psychiatric; neurology; and physical activity and physical fitness. Eligibility criteria for the current study included: living PMRP subjects with known addresses who consented to future contact and were not currently living in a nursing home, available GWAS data from eMERGE I for subjects where age-related cataract, HDL, dementia and resistant hypertension were the primary phenotypes, thus biasi

SUBMITTER: McCarty CA 

PROVIDER: S-EPMC3896802 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature