The transcriptome landscape of Prochlorococcus MED4 and the factors for stabilizing the core genome.

ABSTRACT:

Background

Gene gain and loss frequently occurs in the cyanobacterium Prochlorococcus, a phototroph that numerically dominates tropical and subtropical open oceans. However, little is known about the stabilization of its core genome, which contains approximately 1250 genes, in the context of genome streamlining. Using Prochlorococcus MED4 as a model organism, we investigated the constraints on core genome stabilization using transcriptome profiling.

Results

RNA-Seq technique was used to obtain the transcriptome map of Prochlorococcus MED4, including operons, untranslated regions, non-coding RNAs, and novel genes. Genome-wide expression profiles revealed that three factors contribute to core genome stabilization. First, a negative correlation between gene expression levels an

SUBMITTER: Wang B 

PROVIDER: S-EPMC3898218 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature