Cell-laden microengineered and mechanically tunable hybrid hydrogels of gelatin and graphene oxide.

ABSTRACT: Incorporating graphene oxide inside GelMA hydrogels enhances their mechanical properties and reduces UV-induced cell damage while preserving their favorable characteristics for 3D cell encapsulation. NIH-3T3 fibroblasts encapsulated in GO-GelMA microgels demonstrate excellent cellular viability, proliferation, spreading, and alignment. GO reinforcement combined with a multi-stacking approach offers a facile engineering strategy for the construction of complex artificial tissues.

SUBMITTER: Shin SR 

PROVIDER: S-EPMC3898458 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature