Premature mortality in epilepsy and the role of psychiatric comorbidity: a total population study.

ABSTRACT:

Background

Epilepsy is associated with high rates of premature mortality, but the contribution of psychiatric comorbidity is uncertain. We assessed the prevalence and risks of premature mortality from external causes such as suicide, accidents, and assaults in people with epilepsy with and without psychiatric comorbidity.

Methods

We studied all individuals born in Sweden between 1954 and 2009 with inpatient and outpatient diagnoses of epilepsy (n=69,995) for risks and causes of premature mortality. Patients were compared with age-matched and sex-matched general population controls (n=660,869) and unaffected siblings (n=81,396). Sensitivity analyses were done to investigate whether these odds differed by sex, age, seizure types, comorbid psychiatric diagnosis, and different t

SUBMITTER: Fazel S 

PROVIDER: S-EPMC3899026 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature