The chlamydiales pangenome revisited: structural stability and functional coherence.

ABSTRACT: The entire publicly available set of 37 genome sequences from the bacterial order Chlamydiales has been subjected to comparative analysis in order to reveal the salient features of this pangenome and its evolutionary history. Over 2,000 protein families are detected across multiple species, with a distribution consistent to other studied pangenomes. Of these, there are 180 protein families with multiple members, 312 families with exactly 37 members corresponding to core genes, 428 families with peripheral genes with varying taxonomic distribution and finally 1,125 smaller families. The fact that, even for smaller genomes of Chlamydiales, core genes represent over a quarter of the average protein complement, signifies a certain degree of structural stability, given the wide range of phyloge

SUBMITTER: Psomopoulos FE 

PROVIDER: S-EPMC3899948 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature