Virological efficacy and immunological recovery among Ethiopian HIV-1 infected adults and children.

ABSTRACT:

Background

Introduction of antiretroviral therapy (ART) in sub-Saharan Africa was a hot debate due to many concerns about adherence, logistics and resistance. Currently, it has been significantly scaled up. However as the WHO clinico-immunological approaches for initiation and monitoring of ART in the region lacks viral load determination and drug resistance monitoring, HIV infected adults and children may be at risk for "unrecognized" virologic failure and the subsequent development of antiretroviral drug resistance. This study evaluates the virological efficacy and immunological recovery of HIV/AIDS patients under ART.

Methods

Consecutive HIV-1 infected adults (N = 100) and children (N = 100) who have been receiving ART for up to 6 years at Gondar University Hospital, Ethi

SUBMITTER: Mulu A 

PROVIDER: S-EPMC3900473 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature