Serum leptin and loss of control eating in children and adolescents.

ABSTRACT:

Background

Both insufficiency and resistance to the actions of the adipocyte-derived hormone leptin promote hunger, increased food intake and greater body weight. Some studies suggest that adults reporting binge eating have increased serum leptin compared with those without binge eating, even after adjusting for the greater adiposity that characterizes binge eaters. Pediatric binge or loss of control (LOC) eating are prospective risk factors for excessive weight gain and may predict development of metabolic abnormalities, but whether LOC eating is associated with higher leptin among children is unknown. We therefore examined leptin and LOC eating in a pediatric cohort.

Methods

A convenience sample of 506 lean and obese youth (7-18 years) was recruited from Washington, DC and

SUBMITTER: Miller R 

PROVIDER: S-EPMC3900593 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature