Low-dose aspirin use and recurrent gout attacks.

ABSTRACT:

Objective

To examine the association between cardioprotective use of low-dose aspirin and the risk of recurrent gout attacks among gout patients.

Methods

We conducted an online case-crossover study of individuals with gout over 1 year. The following information was obtained during gout attacks: the onset dates, symptoms and signs, medications, and exposure to potential risk factors, including daily aspirin use and dosage, during the 2-day hazard period prior to the gout attacks. The same exposure information was also obtained over 2-day control periods.

Results

Of the 724 participants analysed, 40.5% took aspirin ≤325 mg/day during either a hazard or a control period. Compared with no aspirin use, the adjusted OR of gout attacks increased by 81% (OR=1.81, 95% CI 1.30

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC3902644 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature