Association between frailty and short- and long-term outcomes among critically ill patients: a multicentre prospective cohort study.

ABSTRACT:

Background

Frailty is a multidimensional syndrome characterized by loss of physiologic and cognitive reserves that confers vulnerability to adverse outcomes. We determined the prevalence, correlates and outcomes associated with frailty among adults admitted to intensive care.

Methods

We prospectively enrolled 421 critically ill adults aged 50 or more at 6 hospitals across the province of Alberta. The primary exposure was frailty, defined by a score greater than 4 on the Clinical Frailty Scale. The primary outcome measure was in-hospital mortality. Secondary outcome measures included adverse events, 1-year mortality and quality of life.

Results

The prevalence of frailty was 32.8% (95% confidence interval [CI] 28.3%-37.5%). Frail patients were older, were more likely to

SUBMITTER: Bagshaw SM 

PROVIDER: S-EPMC3903764 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature