Mortality and morbidity of VLBW infants with trisomy 13 or trisomy 18.

ABSTRACT:

Objective

Little is known about how very low birth weight (VLBW) affects survival and morbidities among infants with trisomy 13 (T13) or trisomy 18 (T18). We examined the care plans for VLBW infants with T13 or T18 and compared their risks of mortality and neonatal morbidities with VLBW infants with trisomy 21 and VLBW infants without birth defects.

Methods

Infants with birth weight 401 to 1500 g born or cared for at a participating center of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network during the period 1994-2009 were studied. Poisson regression models were used to examine risk of death and neonatal morbidities among infants with T13 or T18.

Results

Of 52,262 VLBW infants, 38 (0.07%) had T13 and 128 (0.

SUBMITTER: Boghossian NS 

PROVIDER: S-EPMC3904274 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature