Ontology highlight
ABSTRACT:
SUBMITTER: Do R
PROVIDER: S-EPMC3904346 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Nature genetics 20131006 11
Triglycerides are transported in plasma by specific triglyceride-rich lipoproteins; in epidemiological studies, increased triglyceride levels correlate with higher risk for coronary artery disease (CAD). However, it is unclear whether this association reflects causal processes. We used 185 common variants recently mapped for plasma lipids (P < 5 × 10(-8) for each) to examine the role of triglycerides in risk for CAD. First, we highlight loci associated with both low-density lipoprotein cholester ...[more]