Eight-year weight losses with an intensive lifestyle intervention: the look AHEAD study.

ABSTRACT:

Objective

To evaluate 8-year weight losses achieved with intensive lifestyle intervention (ILI) in the Look AHEAD (Action for Health in Diabetes) study.

Design and methods

Look AHEAD assessed the effects of intentional weight loss on cardiovascular morbidity and mortality in 5,145 overweight/obese adults with type 2 diabetes, randomly assigned to ILI or usual care (i.e., diabetes support and education [DSE]). The ILI provided comprehensive behavioral weight loss counseling over 8 years; DSE participants received periodic group education only.

Results

All participants had the opportunity to complete 8 years of intervention before Look AHEAD was halted in September 2012; ≥88% of both groups completed the 8-year outcomes assessment. ILI and DSE participants lost (mean ±

SUBMITTER: Look AHEAD Research Group 

PROVIDER: S-EPMC3904491 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature