ChAMP: 450k Chip Analysis Methylation Pipeline.

ABSTRACT:

Unlabelled

The Illumina Infinium HumanMethylation450 BeadChip is a new platform for high-throughput DNA methylation analysis. Several methods for normalization and processing of these data have been published recently. Here we present an integrated analysis pipeline offering a choice of the most popular normalization methods while also introducing new methods for calling differentially methylated regions and detecting copy number aberrations.

Availability and implementation

ChAMP is implemented as a Bioconductor package in R. The package and the vignette can be downloaded at bioconductor.org

SUBMITTER: Morris TJ 

PROVIDER: S-EPMC3904520 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature