Comparison of corneal epithelial and stromal thickness distributions between eyes with keratoconus and healthy eyes with corneal astigmatism ≥ 2.0 D.

ABSTRACT:

Purpose

To identify corneal epithelial- and stromal-thickness distribution patterns in keratoconus using spectral-domain optical coherence tomography (SD-OCT).

Patients and methods

We analyzed SD-OCT findings in 20 confirmed cases of keratoconus (group 1) and in 20 healthy subjects with corneal astigmatism ≥ 2 D (group 2). Epithelial and stromal thicknesses were measured at 11 strategic locations along the steepest and flattest meridians, previously located by corneal topography. Vertical mirrored symmetry superimposition was used in the statistical analysis.

Results

The mean maximum keratometry measurements in groups 1 and 2 were 47.9 ± 2.9 D (range, 41.8-52.8) and 45.6 ± 1.1 D (range, 42.3-47.5), respectively, with mean corneal cylinders of 3.3 ± 2.2 D (range, 0.5-9

SUBMITTER: Zhou W 

PROVIDER: S-EPMC3904857 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature