The basal ganglia in perceptual timing: timing performance in Multiple System Atrophy and Huntington's disease.

ABSTRACT: The timing of perceptual events depends on an anatomically and functionally connected network comprising basal ganglia, cerebellum, pre-frontal cortex and supplementary motor area. Recent studies demonstrate the cerebellum to be involved in absolute, duration-based timing, but not in relative timing based on a regular beat. Conversely, functional involvement of the striatum is observed in relative timing, but its role in absolute timing is unclear. This work tests the specific role of the basal ganglia in the perceptual timing of auditory events. It aims to distinguish the hypothesised unified model of time perception (Teki, Grube, & Griffiths, 2012), in which the striatum is a mandatory component for all timing tasks, from a modular system in which they subserve relative timing, with abso

SUBMITTER: Cope TE 

PROVIDER: S-EPMC3905186 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature